2021-04-28, Wednesday - great night & day, so keeping up this GABA-combo despite uncertainty
FEELING Well % / Pain 0-7 DOING
90%/1 Sleep 9h, up 2x (30’), Action 4h30 (TT 6:0), Treatment 1h30 (psych. 1h = 80%/2) (fibro-work 2h55)
Effects of GABA+3: Much less peeing at night despite drinking tons in the evening
Effects of acupressure: Hands not better at first, but seem better today, a night later.
Jaw/tooth pain comes and goes, 60% improved by relaxing jaw, sometimes in background, sometimes gone completely, even when eating hazelnuts or carrots.
GABA-info-page, very helpful to understand, different combination recommended
Why GABA is one of the Best Supplements for Anxiety and Sleep (Updated – Natural Stacks
You should never take a GABA supplement on its own! It actually won’t work!
It’s strange that more people don’t know about this neurotransmitter, since it’s the most common one in our central nervous systems!
When you have a “fight or flight response” — your heart beats faster and your stomach knots up — GABA is what allows your brain to calm down again afterwards.
This is because GABA is responsible for putting the brakes on messages passing between our neurons, telling them not to fire, and thereby blocking stress response messages from being passed along to the rest of the body.
This explains why low levels of GABA or disruption of GABA receptors is associated with some forms of epilepsy and various other physical and mental disorders characterized by excitability.
So why doesn’t it work all the time?
Under normal conditions, the excitatory and inhibitory systems work in harmony to keep the nervous system in balance.
But when faced with chronic stress and fatigue, the neurotransmitters can get out of synch.
The body’s natural stress response overpowers the amount of GABA that the body can produce to compensate.
These include high blood pressure, sweating, increased secretion of gastric acid and activity of the large intestine.
Part of the production pathway for GABA takes place in the mitochondria in our cells. Stress causes inflammation and oxidative stress and, together with a nutritional imbalance, it affects mitochondrial health.
While there’s no food that contains GABA, you can certainly eat foods that provide glutamate and glutamic acid, the precursors that your body uses to make GABA.
Foods with lots of glutamate and glutamic acid include grass-fed meats, eggs, dairy products, fish, sea vegetables, tomatoes and mushrooms.
Other supplements which have been shown to increase GABA or enhance its function include L-thiamine, the amino acid taurine, and certain herbs including kava, passionflower and lemon balm.
The following dosages are recommended:
General stress relief
650 -800 mg per day
Divide into three or four doses during the day
250 – 650 mg 3x per day
Maximum dose 1950 mg per day
250 – 650 mg daily
Take just before sleep
500 – 1000 mg
Take just before sleep. High dose ensures that more crosses the BBB
A recent study on humans showed that a supplement combining both GABA and 5-HTP reduced the time it took to fall asleep, increased the duration of sleep, and improved sleep quality. 
GRAPE SEED EXTRACT(33MG)
Does GABA helping mean I have a leaky brain and this is all wrong?
How to Increase GABA and Lower Glutamate
According to Dr. Datis Kharazzian, a brain expert, if you have any effect from GABA, (positive or negative) that means you have a leaky brain. In his book, Why Isn’t My Brain Working, he explains that in a healthy brain, the junctions in the blood-brain barrier only permit nanoparticles to pass through. GABA “exceeds the nanoparticle size and does not have a blood-brain barrier transport protein.” It should not be able to cross the blood-brain barrier. If it does, then this suggests there is a leaky brain.
As a matter of fact, Dr. Kharrazian uses GABA supplementation as a screening tool to determine whether one has a leaky brain or not, calling it the GABA Challenge Test. He also states you shouldn’t take GABA supplementation, even if you have a positive effect, “because you risk shutting down your GABA receptor sites.” This is evidenced by the fact that many people experience withdrawal when they come off a GABA supplement. The fact that withdrawal is occurring tells us that the brain is downregulating responsiveness to GABA in response to the GABA supplementation. I do not encourage the use of GABA supplements unless one is coming off a benzo and uses it temporarily to get from point A to point B in recovery. If you have no effect from GABA, this is a good sign, you most likely to do not have a leaky brain. If a leaky brain is present, then many other harmful substances can be crossing the blood-brain barrier and causing additional problems.
Integrative Holistic Health Coach - Cynthia Perkins, M.Ed.
(Well in % / Pain incl. Gut 0-10) (Sleep, Fibro-‘Work’, Work Digi & Live, Activity, Treatment)
90%/1 Sleep 21:30- (80%/2, very tired) 0:40 (p.i.)25’ 4:00p 7:00 (p) 9h, up 2x (30’). fw7:05:20’ 7:30: RR 112/72 59. Measure more 7:40 I cd get up, but feel like resting more, bit unstable, slightly shaky, praps it’s just the bp tho. RR 7:40 110/74 61.
RR: 9:30 141/80 61 after high energy back exercise. music lesson 1h+20’. work 60’. TT 6:0 1h + cycling. Cook broccoli, eat, psychologist, shop, fibro-work 16:30-17:15=35’, work.
Fibro-work: 7:05:20’ 7:45:1h40 16:30:35’ 20:55:20’ =2h55
Timing, AuTr, palpate, cold shower, stretch
Workout, breath-hold, Neck, Yoga
Docs/Diagnoses: My psychologist does mainly Gestalt therapy. After the news part about new easier work & the positive effect of GABA we concentrated on positive tension vs. strain & tautness, with childhood and relationship as examples and connections, & concentration on feelings during that, in future practicing coping mechanisms whilst talking about that. It was a strain - hope it’ll do summink.
AT = Autogenic Training, cold/FCS = Flash Cold Shower (20’’) , ex = exercises, HWB = Hot water bottle, breath-hold/WHM-B-H = Wim Hof Method Breath-Holding, slp = sleep.
Reasons for getting up lbu: lower back unrest, p: pee, i: ideas. PsA = Psoriatic Arthritis-suspicion
fw = fibro-work
Pain 7 = crying (/out) point